Research Review: Machine learning ensemble identifies distinct age-related response to spaceflight in mammary tissue
Introduction Spaceflight introduces extreme stressors like microgravity and radiation, which impact biological systems differently based on age. In female mammals, these effects may increase the risk of pathologies such as breast cancer. This study leverages a machine learning ensemble to explore gene expression in young and old female mice exposed to spaceflight, uncovering age-dependent molecular […]
Differential Expression (DE) Analysis in RNA-seq
Differential Expression (DE) analysis is a foundational technique in the field of transcriptomics, allowing researchers to identify genes that exhibit significant changes in expression between two or more biological conditions. Whether exploring the genetic basis of diseases, assessing drug response, or understanding fundamental cellular processes, DE analysis using RNA sequencing (RNA-seq) data provides a high-resolution […]