In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells
Link to the paper: https://pubmed.ncbi.nlm.nih.gov/35470505/ Ionizing radiation, a known health risk, was studied for its impact on DNA methylation-based markers of biological age in human bronchial epithelial cells. High-LET 56Fe ions were significantly associated with accelerated epigenetic clock epiTOC2, indicating potential utility of epigenetic clocks in monitoring the health effects of galactic cosmic radiation. The […]
Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration
Plants like Arabidopsis thaliana can grow in lunar regolith from Apollo missions, but they face challenges in development and show stress morphologies. Plants grown in lunar soils exhibit gene expression related to ionic stresses, similar to reactions to salt, metal, and reactive oxygen species, indicating the need for further understanding and mitigation for efficient use […]
Diacylglycerol kinase is downregulated in the Drosophila Seizure Mutant during Spaceflight
Related Articles Potential of Diacylglycerol Kinase in Biomedical Research Seizures The study investigates the downregulation of diacylglycerol kinase in a Drosophila mutant during spaceflight, potentially impacting longevity . Using omics data from Drosophila reared in microgravity, the research aims to identify critical targets for promoting longevity in space missions, highlighting the importance of understanding gene […]